Background/Methods:
- DHG-G34 is an incurable brain cancer of adolescents and young adults, with no targeted treatment•DHG-G34 is susceptible to localized genome instability near mutated nucleosomes (A)
- Uncovering mechanisms of immune escape may lead to a shift in treatment approach
- Caris Life Sciences has accumulated a large cohort of DHG-G34 omics, permitting an exploration of the molecular and immune landscapes