Prostate cancer (PCa) is the most common non-skin cancer among American men. MicroRNAs (miRNAs) are critical posttranscriptional regulators and involved in prostate cancer tumorigenesis. The aim of this study is to identify a PCa-specific expression profile of miRNAs from plasma to guide prostate cancer diagnosis and therapeutic treatment.
- We discovered a unique expression profile of miRNA detectable in the plasma from prostate cancer patients.
- Extracted RNA from the pellets of anti-Ago2 immunoprecipitations can enhance the detection of miRNA.
- Expand study to confirm these findings are needed.