SGO 2015 Plenary - Identification of Potential Therapeutic Targets by Molecular and Genomic Profiling of 628 Cases of Uterine Serous Carcinoma | Caris Life Sciences
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SGO 2015 Plenary – Identification of Potential Therapeutic Targets by Molecular and Genomic Profiling of 628 Cases of Uterine Serous Carcinoma

– Caris Life Sciences

Presentation

Objectives

  • We aim to identify patterns of molecular and genetic change in USC tumors
  • Offer potential targetable pathways for future therapeutic study
  • Identify patients that may benefit from the large number of biological therapeutics available

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  • Molecular characterization of 361 cases of uterine carcinosarcomas reveal alterations in the DNA repair and PI3K pathways as potential therapeutic targets

    – Caris Life Sciences

    Poster

    Background: Uterine carcinosarcomas (malignant mixed Müllerian tumors or MMMT) are rare endometrial cancers (EC) composed of epithelial and mesenchymal components. MMMTs exhibit aggressive behavior with… […]

  • Results of comprehensive molecular profiling of gliomas and the potential therapeutic implications

    – Caris Life Sciences

    Poster

    Background Gliomas are the most common type of primary brain tumors with underlying molecular heterogeneity contributing to differential treatment response. Our retrospective study was designed… […]
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