Key Finding:
Consistent with observations in small-cell lung cancer, YAP1 expression positively correlates with the ‘T-cell inflamed’ phenotype in 12 additional cancer types.
– Caris Life Sciences
Key Findings: Small-cell lung cancer (SCLC) subtypes based on transcription factor expression patterns of ASCL1, NEUROD1, YAP1 and POU2F3, and the resultant four subtypes SCLC-A,… […]
– Caris Life Sciences
Background: The dominant expression of four lineage-defining transcription factors (ASCL1, NEUROD1, YAP1, or POU2F3) has enabled the classification of small cell lung cancer (SCLC) into four subtypes (SCLC-A/N/Y/P, respectively).… […]
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