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Exploring the nuances between BRCA1 and 2: a multiomic analysis

– Caris Life Sciences

Poster

Key Finding:

Metabolic and immune response pathways are differentially regulated between BRCA1 mutant, BRCA2 mutant, and homologous recombination wild-type high-grade serous ovarian cancers. 

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  • Adult Granulosa Cell Tumor with Rare Pulmonary Presentation

    – Caris Life Sciences

    Manuscript

    Abstract Adult granulosa cell tumor (GCT) is an uncommon sex cord-stromal neoplasm of the ovary. It typically demonstrates locoregional spread, and disease outside of the… […]

  • Characterization of plasma cell-free DNA variants as of tumor- or clonal hematopoiesis-origin in 16,812 advanced cancer patients

    – Caris Life Sciences

    Manuscript

    Abstract  Purpose: Plasma-based liquid biopsy tests can detect tumor-specific genetic alterations and offer many advantages that complement tissue-based Comprehensive Genomic Profiling (CGP). However, age-related clonal hematopoiesis… […]
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