Exploring molecular profiles of uterine carcinosarcoma with alterations in the chromatin remodeling pathway | Caris Life Sciences
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Exploring molecular profiles of uterine carcinosarcoma with alterations in the chromatin remodeling pathway

Background: In a preliminary data analysis to identify prognostic molecular biomarkers in uterine carcinosarcoma (UCS), we found that alterations in KMT2C, a gene involved in the chromatin remodeling pathway, correlated with improved survival. We sought to explore relevant biomarkers of KMT2C-mutated (KMT2C-mut) tumors compared to wildtype (KMT2C-wt) tumors.

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