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Distinct molecular landscape between endometrioid and non-endometrioid uterine carcinoma

– Caris Life Sciences

Poster

Background: Endometrial carcinoma (EC) is typically divided into endometrioid (Type I) and nonendometrioid (Type II) subtypes, despite considerable heterogeneity within each phenotype. We examined molecular alterations between Type I and Type II EC to better understand differences and identify optimal treatment strategies.

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  • Differences in the molecular landscape of uterine cancer between African American and Caucasian patients

    – Caris Life Sciences

    Poster

    Results of a tumor profiling study of uterine cancer specimens revealed that African-American women were significantly more likely to have uterine cancer characterized as serous… […]

  • PD-1 and PD-L1 expression in 1599 gynecological malignancies – implications for immunotherapy

    – Caris Life Sciences

    Poster

    Objectives: T-cell suppression via PD-1/PD-L1 interactions plays a central role in cancer progression and survival, making PD-1/PD-L1 attractive therapeutic targets. Clinical trials involving PD-1/PD-L1-targeted immunotherapies… […]
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