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DEFB1 gene expression and the molecular landscape of colorectal cancer (CRC)

– Caris Life Sciences

Poster

Key Finding:

DEF1B gene expression in colorectal cancer is associated with a distinct mutational profile, CMS, immune biomarkers, and tumor microenvironment cell infiltration. 

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  • Loss of O6-Methylguanine-DNA Methyltransferase Protein Expression by Immunohistochemistry Is Associated With Response to Capecitabine and Temozolomide in Neuroendocrine Neoplasms

    – Caris Life Sciences

    Manuscript

    Abstract Background A recent prospective phase II study (ECOG-ACRIN E2211) demonstrated that MGMT deficiency was associated with a significant response to capecitabine and temozolomide (CAPTEM)… […]

  • Clinical and Molecular Characterization of FAP and SPP1 in Colorectal Cancer (CRC), CALGB (Alliance)/SWOG 80405 and Real-world Data

    – Caris Life Sciences

    Poster

    Background […]
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