CRTC1::TRIM11-fusion tumor with rare sinonasal presentation and locally aggressive disease course | Caris Life Sciences
Home / Research / Publications / CRTC1::TRIM11-fusion tumor with rare sinonasal presentation and locally aggressive disease course

Publications

CRTC1::TRIM11-fusion tumor with rare sinonasal presentation and locally aggressive disease course

Introduction

  • Cutaneous melanocytic tumor with CRTC1::TRIM11 fusion (CMTCT) is a rare dermatological neoplasm that has not yet been formally recognized by the World Health Organization.
  • At present, our knowledge of this disease is limited to single reports and a series of 41 cases with limited follow-up information.
  • It is typically described as a skin lesion expressing melanocytic makers, often leading to its misdiagnosis as melanoma or clear cell sarcoma.
  • CMTCT is regarded as an indolent tumor with infrequent recurrence after complete surgical excision.
  • However, we present a case with uncommon sinonasal presentation and metastasis after multiple resections.

Download Publication
Learn More
Name(Required)