Comprehensive characterization of androgen receptor in male breast cancer | Caris Life Sciences
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Comprehensive characterization of androgen receptor in male breast cancer

Background

  • Male breast cancer (BC) accounts for less than 1% of new BC cases annually.
  • Androgen receptor (AR), a member of steroid and nuclear receptor superfamily is emerging as an important factor in pathobiology of BC.
  • While the estrogen receptor (ER) is well-studied in BC, the role of the AR is less understood, particularly in male patients.
  • Here, we aimed to characterize the molecular and immunological features of AR gene expression in male BC.

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