Clinicopathologic characteristics of HRAS mutant head and neck squamous cell carcinoma (HNSCC). | Caris Life Sciences
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Clinicopathologic characteristics of HRAS mutant head and neck squamous cell carcinoma (HNSCC).

– Caris Life Sciences

Poster

Key Finding:

Mutations in HRAS are associated with poor outcomes and higher MAPK activation, PD-L1 levels, tumor mutational burden, and IFN scores in head and neck squamous cell carcinomas. 

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  • Molecular characteristics of HRAS mutated non-small cell lung cancer

    – Caris Life Sciences

    Poster

    Background • Alterations in the RAS pathway have been linked to tumorigenesis, cellular apoptosis, metabolism and angiogenesis. Mutations of KRAS in non-small cell lung cancer… […]

  • Biomarker Expression in Head and Neck Squamous Cell Carcinoma – Implications for Therapy

    – Caris Life Sciences

    Poster

    Background Head and neck squamous cell carcinoma (HNSCC) is an aggressive disease with an unpredictable prognosis. Failure of first-line treatment is common, thus additional therapeutic… […]
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