- Cancer cachexia is characterized by progressive weight loss and skeletal muscle degradation, contributing to 33% of pancreatic ductal adenocarcinoma (PDAC) deaths.
- Novel therapeutics targets of myostatin in the myostatinactivin pathway have been shown to reverse cachexia.
- Here, we present a large clinical and molecular characterization of the myostatin-activin pathway in PDAC
Publications
Characterization of the cachexia pathway in pancreatic ductal adenocarcinoma
– Caris Life Sciences