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Home / Research / Publications / Characterization of NY-ESO-1 gene expression in gastric cancer (GC)

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Characterization of NY-ESO-1 gene expression in gastric cancer (GC)

– Caris Life Sciences

Poster

Key Finding:

Gastric cancers with high expression of NY-ESO-1 have a high expression of immune related genes and a T-cell inflamed signature (TIS) score, which predicts benefit from anti-PD-1 treatment. 

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  • Claudin 18 (CLDN18) gene expression and related molecular profile in gastric cancer (GC)

    – Caris Life Sciences

    Poster

    Key Finding: Gastric cancers with high CLDN18 expression display distinct genomic and transcriptomic alterations in immune biomarkers and immune cell infiltration in the tumor microenvironment. […]

  • Association of DNA damage response and repair gene (DDR) mutations and microsatellite instability (MSI), PD-L1 expression, tumor mutational burden (TMB) in gastroesophageal cancers

    – Caris Life Sciences

    Poster

    BACKGROUND DNA damage response and repair genes (DDR) encode proteins that assist in homology-directed repair. These proteins interact with other DNA repair proteins and form… […]
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