Characterization of MET exon 14 skipping alterations (METex14) in non-small cell lung cancer (NSCLC) using whole transcriptome sequencing (WTS) | Caris Life Sciences
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Characterization of MET exon 14 skipping alterations (METex14) in non-small cell lung cancer (NSCLC) using whole transcriptome sequencing (WTS)

– Caris Life Sciences

Poster

Key Finding:

In non-small cell lung cancer, splicing alterations and MET co-amplification result in high MET expression. 

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  • Characterization of MET Exon 14 Skipping Analog (Y1003) in Non-Small Cell Lung Cancer (NSCLC)

    – Caris Life Sciences

    Poster

    Abstract Introduction: Genomic alterations in the juxtamembrane exon 14 splice sites in NSCLC lead to increased MET stability and oncogenesis. We present the largest cohort study… […]

  • Characterization of MET Exon 14 Skipping Alterations (METex14) in Non-Small Cell Lung Cancer (NSCLC) using Whole Transcriptome Sequencing (WTS).

    – Caris Life Sciences

    Manuscript

    Abstract Introduction Genomic alterations in the juxtamembrane exon 14 splice sites in NSCLC lead to increased MET stability and oncogenesis. We present the largest cohort… […]
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