Background
Patients with sRCC have a have a poor prognosis and decreased likelihood of response to targeted therapy or IL-2. Predictive biomarkers of response are lacking in sRCC. We evaluated a cohort of RCC patients to identify potentially actionable recurrent molecular aberrations.
– Caris Life Sciences
Abstract Purpose: 10-15% of prostate cancers (PCa) harbor recurrent FOXA1 aberrations whereby the alteration type and the effect on the forkhead( FKH) domain impacts protein-function. We developed… […]
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