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Molecular analysis of non-epithelial ovarian cancer by histologic subtype

– Caris Life Sciences

Poster

Abstract
Background: Non-epithelial malignancies of the ovary account for <2%–4% of all ovarian tumors. The classification of nonepithelial ovarian cancer can be broadly divided into two histological subtypes, ovarian germ cell tumors (OGCTs) and ovarian sex cord stromal tumors (OSCSTs).

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  • PD-1 and PD-L1 expression in 1599 gynecological malignancies – implications for immunotherapy

    – Caris Life Sciences

    Poster

    Objectives: T-cell suppression via PD-1/PD-L1 interactions plays a central role in cancer progression and survival, making PD-1/PD-L1 attractive therapeutic targets. Clinical trials involving PD-1/PD-L1-targeted immunotherapies… […]

  • BRCA1 and BRCA2 mutations in 1691 epithelial ovarian tumors identify subgroups with distinct molecular characteristics

    – Caris Life Sciences

    Poster

    Background : Increasing data has shown that ovarian cancer patients carrying BRCA1 and BRCA2 mutations, both somatic and germline, experience a survival advantage and are… […]
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