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GPR171, a Prognostic Marker of Improved Survival in Cervix Cancer – A Deep South Consortium in Oncology (DSCO) Project

Background

  • Women of poorer socioeconomic status are more likely to develop cervix cancer. 
  • Molecular markers of chronic stress have been shown to have an effect on tumor immunity. 
  • The tumor immune microenvironment can contribute to T-cell dysfunction. 
  • GPR171 is a G-protein coupled-receptor that plays a role in tumor immunity. 
  • The role of GPR171 in the immune landscape of cervix cancer has not been studied. 
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