Capicua (CIC) mutations in gliomas are associated with MAPK activation exposing a potential therapeutic target

Authors:

Sourat Darabi, Joanne Xiu, Daniel Magee, Santosh Kesari, Jose Arganda Carrillo, Sonikpreet Aulakh, Kyle Walsh, Soma Sengupta, Ashley Love Sumrall, David Spetzler, Michael J. Glantz, Wolfgang Michael Korn, Michael J. Demeure

Key Finding:

CIC mutations occur frequently in oligodendrogliomas and are associated with favorable prognostic markers. 

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