Background: Histologic heterogeneity of tumors is well documented; however, the molecular heterogeneity is not well understood, especially relative to driver mutations within clonal populations and their prognostic and predictive value.
– Caris Life Sciences
Abstract Purpose: 10-15% of prostate cancers (PCa) harbor recurrent FOXA1 aberrations whereby the alteration type and the effect on the forkhead( FKH) domain impacts protein-function. We developed… […]
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